This article examines the development of Uzbekistan’s textile and apparel industry through the lens of its organizational-economic mechanism and identifies the main directions for its improvement under current conditions. The study analyzes sectoral dynamics for 2016-2025, focusing on production trends, structural change, and the industry’s role in national industrial development. The results show that recent sectoral growth has been driven mainly by real output expansion rather than by price effects, while the ARIMA (0,2,1) model indicates continued growth through 2028. On this basis, the article substantiates practical directions for modernization, deeper processing, export competitiveness, and stronger coordination within the industry.